Search Result

Search Results for " carbonic anhydrase ix "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T63305	Carbonic anhydrase inhibitor 6		Carbonic Anhydrase
	Carbonic anhydrase inhibitor 6 is a potent human carbonic anhydrase (hCA) inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of diseases caused by abnormalities in carbonic anhydrase.		Carbonic Anhydrase
T67775	Enpp/Carbonic anhydrase-IN-1		PDE , Carbonic Anhydrase
	Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase. Enpp/Carbonic anhydrase-IN-1 exhibits IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectiv...		PDE , Carbonic Anhydrase
T77631	Enpp/Carbonic anhydrase-IN-2		Apoptosis , PDE , Carbonic Anhydrase
	Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-I...		Apoptosis , PDE , Carbonic Anhydrase
T36758	CAIX Inhibitor S4	S4	Carbonic Anhydrase
	CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM.		Carbonic Anhydrase
T2017	U-104	NSC-213841,MST-104	Carbonic Anhydrase
	U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).		Carbonic Anhydrase
T76684	Girentuximab	cG250,WX-G250,G250	Carbonic Anhydrase
	Girentuximab (G250) is a potent anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anticancer activity for the study of uroepithelial carcinoma PET (ZiPUP).		Carbonic Anhydrase
T60351	Acetazolamide sodium	OT-302 sodium	Carbonic Anhydrase
	Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA)IX inhibitor with diuretic, antigonococcal, and antihypertensive activity and may be used for indications such as epilepsy, glaucoma, edema, and alt...		Carbonic Anhydrase
T73177	HCAII-IN-9		Carbonic Anhydrase
	hCAII-IN-9 is a potent carbonic anhydrase inhibitor that inhibits hCA II, hCA IX, and hCA XII with IC50s of 1.18 μM and 0.17 μM , and 2.99 μM , respectively. hCAII-IN-9 is not blood-brain barrier permeable.		Carbonic Anhydrase
T71877	GC-204
	GC-204 is a selective inhibitor of carbonic anhydrase ix (caix)
T35066	VM4-037	VM4 037,VM4037
	VM4-037 is a PET imaging agent used for carbonic anhydrase IX.
T35067	VM4-037 F-18	(F18)Vm-4-037,VM4037 F-18,VM4 037 F-18
	VM4-037 F-18 is a fluorinated PET imaging agent used for carbonic anhydrase IX.
T70360	STX2845
	STX2845 is a nonsteroidal Sulfamate Derivative that inhibit Carbonic Anhydrase IX (Ki = 2 nM)
T63731	Carbonic anhydrase inhibitor 9
	Carbonic anhydrase inhibitor 9 is a potent inhibitor of carbonic anhydrase (CA) that acts on hCA II (Ki: 56.4 nM) and IX (Ki: 56.9 nM) and exhibits antiproliferative effects.
T61982	Human carbonic anhydrase II-IN-2
	Human carbonic anhydrase II-IN-24 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor. Human carbonic anhydrase II-IN-24 shows K i s of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respective...
T63005	Carbonic anhydrase inhibitor 11
	Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor that acts on CA II (Ki: 40 nM), CA IX (Ki: 39 nM) and CA XII (Ki: 900 nM).
T62976	Carbonic anhydrase inhibitor 5
	Carbonic anhydrase inhibitor 5 is a potent and selective inhibitor of human carbonic anhydrase (hCA), acting on hCA II (IC50: 42.9 nM), hCA IX (IC50: 47.6 nM) and hCA XII (IC50: 6.7 nM).
T62666	Carbonic anhydrase inhibitor 7
	Carbonic anhydrase inhibitor 7 is a potent inhibitor of human carbonic anhydrase (hCA), acting on hCA IX (Ki: 6.5 nM), hCA II (Ki: 7.1 nM), hCA XII (Ki: 72.1 nM) and hCA I (Ki: 255.8 nM).
T72164	Enpp/Carbonic anhydrase-IN-2
	Enpp/Carbonic anhydrase-IN-2 is a potent Enpp and carbonic anhydrase inhibitor with IC 50 s of 1.13, 1.07, 0.74, 0.33, 0.68 for NPP1, NPP2, NPP3, CA-IX, CA-XII respectively. Enpp/Carbonic anhydrase-IN-2 shows antiprolif...
T61981	Human carbonic anhydrase II-IN-1
	Human carbonic anhydrase II-IN-1 (Compound S-13) is a potent human carbonic anhydrase II (hCA II) inhibitor. Human carbonic anhydrase II-IN-1 shows Kis of 4.4 nM, 9.2 nM, 480.2 nM and 14.7 nM for hCA II, I, IV and IX, re...
T62026	HCAIX-IN-11
	hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor. hCAIX-IN-11 shows K i s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively.
T61263	HCA IX-IN-1
	hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase ( hCA ) inhibitor with K i values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity [1]...
T61032	Carbonic anhydrase inhibitor 10
	Carbonic anhydrase inhibitor 10 can be used in the research of cancer that shows anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 is a potent inhibitor o...
T83137	ALP/Carbonic anhydrase-IN-1		Carbonic Anhydrase
	Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline phosphatase (ALP). It exhibits inhibitory IC50 values of 0....		Carbonic Anhydrase
T61842	Carbonic anhydrase inhibitor 14
	Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibit...
T63158	HCAIX-IN-10
	hCAIX-IN-10 (Compound 6i) is a selective inhibitor of carbonic anhydrase IX and XII, acting on hCA IX (Ki: 61.5 nM) and hCA XII (Ki: 586.8 nM). hCA IX and hCA XII are transmembrane isoforms of carbonic anhydrase that act...
T74955	HCAIX-IN-13
	hCAIX-IN-13 (Pt2), a Carbonic Anhydrase IX (CAIX) inhibitor, demonstrates a notable IC50 value of 6.57 μM, efficiently impeding cancer cell growth and promoting apoptosis. It is valuable for cancer research [1].
T63753	HCAIX-IN-3
	hCAII-IN-3 (compound 7e) is a selective and potent carbonic anhydrase (CA II/IX) inhibitors with their Kis values of 124.2 and 30.5 nM, respectively. hCAII-IN-1 has shown investigational potential for cancer disease.
T62755	HCAIX-IN-2
	HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).
T61164	HCAII-IN-3
	hCAII-IN-3 (Compound 16) is an inhibitor of human carbonic anhydrase (hCA). It exhibits high affinity for hCA I, hCA II, hCA IX, and hCA XII, with Ki values of 403.8 nM, 5.1 nM, 10.2 nM, and 5.2 nM, respectively. Notably...
T70813	DTP348
	DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide componen...
T73029	HCAIX-IN-15		Carbonic Anhydrase
	hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer activity suitable for cancer research [1].		Carbonic Anhydrase
T61282	HCAI/II-IN-2
	hCAI/II-IN-2 (compound 2b) is a highly effective dual inhibitor of human carbonic anhydrase I and II (hCA I/II), with Ki values of 40.97 nM, 15.15 nM, and 61.88 nM for hCA I, hCA II, and hCA IX, respectively. With its an...
T62101	HCAXII-IN-2
	hCAXII-IN-2 (compound 5i) is a potent inhibitor of human carbonic anhydrase XII (hCA XII) (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity against hCA I and hCA II.
T63631	HCAII-IN-2
	hCAII-IN-2 is a cytoplasmic human carbonic anhydrase (hCA) inhibitor that acts on hCA I (Ki: 261.4 nM), hCA II (Ki: 3.8 nM), hCA IX (Ki: 19.6 nM) and hCA XII (Ki: 45.2 nM).
T63764	HCA XII/II/IX-IN-1
	hCA XII/II/IX-IN-1 is a potent inhibitor of human carbonic anhydrase (hCA) and is able to act on hCA I (IC50: 2.6 μM), hCA II (IC50: 0.004 μM), hCA IX (IC50: 0.005 μM) and hCA XII (IC50: 0.001 μM). hCA XII/II/IX -IN-1 ex...
T74331	HCAII-IN-7
	Compound R-13, also known as hCAII-IN-7, is a powerful inhibitor of human carbonic anhydrase (hCA), exhibiting inhibition constants (Ki) of 60.7 nM for hCA I, 320.7 nM for hCA II, 2298 nM for hCA IV, and 35.2 nM for hCA ...
T79451	WES-1		Carbonic Anhydrase
	WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines, including leukemia (K-562 and MOLT-4), non-small cell lung cance...		Carbonic Anhydrase
T63752	HCAII-IN-1
	hCAII-IN-1 (compound 7f) is a selective and potent inhibitor of carbonic anhydrase (CA II/IX) with their Kis values of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has shown investigational potential for cancer disease.
T74486	HCAIX-IN-17
	Compound 6f, also known as hCA IX-IN-1, is a human carbonic anhydrase (hCA) inhibitor that exhibits varying inhibitory effectiveness across different hCA isoforms, with K i values of 331.4 nM for hCA I, 28.4 nM for hCA I...
T78729	HCAIX/VII-IN-1		Carbonic Anhydrase
	hCAIX/VII-IN-1 is a selective inhibitor of human carbonic anhydrase isoforms VII and IX. It displays inhibitory activity against hCA I, II, IV, VII, and IX, with respective K_i values of 336.2 nM, 185.8 nM, 1055 nM, 35.6...		Carbonic Anhydrase
T79748	HCAIX/XII-IN-7		Carbonic Anhydrase
	Compound 3e (hCAIX/XII-IN-7) is a potent inhibitor of human carbonic anhydrase (hCA) isozymes IX and XII, displaying inhibitory constants (Kis) of 503.7 nM for hCA IX and 59 nM for hCA XII, while also showing activity ag...		Carbonic Anhydrase
T72840	HCAIX/XII-IN-6
	hCAIX/XII-IN-6, an orally active carbonic anhydrase (CA) inhibitor, targets human CA isoforms hCA I, II, IV, IX, and XII with inhibition constants (K i) of 6697 nM, 2950 nM, 4093 nM, 4.1 nM, and 7.7 nM, respectively. Thi...
T74330	HCAII-IN-6
	hCAII-IN-6 (Compound S-13), a potent inhibitor of human carbonic anhydrase II (hCA II) with a K i of 4.4 nM, also exhibits inhibitory activity against other hCA isoforms, namely I, IV, and IX, with K i values of 9.2 nM, ...
T74978	DPP IV/hCA II-IN-1
	DPP IV/hCA II-IN-1 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP IV) and carbonic anhydrase (CA), exhibiting an IC50 of 0.049 μM for DPP IV and K_i values of 0.0361, 0.0428, 0.0941, 0.1328, 0.2615, and...
T79540	HCA/VEGFR-2-IN-1		Carbonic Anhydrase
	hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2). It exhibits Ki values of 4.7 nM for hCA XII and 8.3 nM...		Carbonic Anhydrase
T60602	HCAIX/XII-IN-5
	hCAIX/XII-IN-5 (Coumarin 9a) is an inhibitor of carbonic anhydrase (CA) that shows excellent hCA IX/XII selectivity with Kis of 93.3 and 85.7 nM over hCA I and hCA II, respectively. hCAIX/XII-IN-5 has anti-proliferative ...
T78705	COX-2-IN-30		COX
	COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 = 10.4 μM), as well as 5-lipoxygenase (5-LOX; IC50 = 2.4 μM). ...		COX
T63400	HA2A/hCA XII modulator 1
	hA2A/hCA XII modulator 1 is a potent antagonist of the hA2A adenosine receptor (hA2AAR), a triazolopyrazine that acts on hA2AAR (Ki: 6.4 nM), hA1AR (Ki: 4.819 μM), and hA3AR (Ki>30 μM). hA2A/hCA XII modulator 1 Also a po...
T35876	Chlorthalidone Impurity G
	Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects. Chlorthalidone is a thiazide-like diuretic that inhibits the Na+/Cl- cotran...

Compounds

Carbonic anhydrase inhibitor 6

T63305

Synonym:

Target: Carbonic Anhydrase

Enpp/Carbonic anhydrase-IN-1

T67775

Synonym:

Target: PDE, Carbonic Anhydrase

Enpp/Carbonic anhydrase-IN-2

T77631

Synonym:

Target: Apoptosis, PDE, Carbonic Anhydrase

CAIX Inhibitor S4

T36758

Synonym: S4

Target: Carbonic Anhydrase

U-104

T2017

Synonym: NSC-213841,MST-104

Target: Carbonic Anhydrase

Girentuximab

T76684

Synonym: cG250,WX-G250,G250

Target: Carbonic Anhydrase

Acetazolamide sodium

T60351

Synonym: OT-302 sodium

Target: Carbonic Anhydrase

hCAII-IN-9

T73177

Synonym:

Target: Carbonic Anhydrase

Synonym: VM4 037,VM4037

Target:

VM4-037 F-18

T35067

Synonym: (F18)Vm-4-037,VM4037 F-18,VM4 037 F-18

Carbonic anhydrase inhibitor 9

T63731

Synonym:

Target:

Human carbonic anhydrase II-IN-2

T61982

Synonym:

Target:

Carbonic anhydrase inhibitor 11

T63005

Synonym:

Target:

Carbonic anhydrase inhibitor 5

T62976

Synonym:

Target:

Carbonic anhydrase inhibitor 7

T62666

Synonym:

Target:

Enpp/Carbonic anhydrase-IN-2

T72164

Synonym:

Target:

Human carbonic anhydrase II-IN-1

Carbonic anhydrase inhibitor 10

T61032

Synonym:

Target:

ALP/Carbonic anhydrase-IN-1

T83137

Synonym:

Target: Carbonic Anhydrase

Carbonic anhydrase inhibitor 14

Target: Carbonic Anhydrase

Target: Carbonic Anhydrase

Target: Carbonic Anhydrase

hCAIX/XII-IN-7

T79748

Synonym:

Target: Carbonic Anhydrase

Target: Carbonic Anhydrase

hA2A/hCA XII modulator 1

T63400

Synonym:

Target:

Chlorthalidone Impurity G

T35876

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T40611	(E)-Dehydrodiconiferyl alcohol
	(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibi...

Natural Products

(E)-Dehydrodiconiferyl alcohol

T40611

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00690	Carbonic Anhydrase 9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.5 kDa and the accession number is A0A0S2Z3D0.
TMPY-00689	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.7 kDa and the accession number is A0A0S2Z3D0.
TMPY-02989	Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.6 kDa.
TMPY-02990	Carbonic Anhydrase 9 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is A0A8C0RHE4.
TMPY-01700	Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is Q3UUZ9.
TMPY-06939	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 69.51 kDa and the accession number is NP_001207.2.
TMPY-06936	Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Carbonic Anhydrase 9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 44.23 kDa and the accession number is NP_001207.2.
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPK-00283	CA9/Carbonic Anhydrase IX Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tu...
TMPJ-00283	Carbonic Anhydrase 9 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzym...